Carbapenem-resistant enterobacteriaceae ( CRE) or Carbapenemase-producing Enterobacteriaceae (CPE), are gram-negative bacteria that are nearly resistant to the carbapenem class of antibiotics, considered the "drug of last resort" for such infections. Enterobacteriaceae are common commensals and infectious agents. Experts fear CRE as the new "superbug". The bacteria can kill up to half of patients who get bloodstream infections. Tom Frieden, head of the Centers for Disease Control has referred to CRE as "n..
In shipping, break bulk cargo or general cargo are goods that must be loaded individually, and not in intermodal containers nor in bulk cargo as with oil or grain. Ships that carry this sort of cargo are often called general cargo ships. The term break bulk derives from the phrase breaking bulk—the extraction of a portion of the cargo of a ship or the beginning of the unloading process from the ship's holds. These goods may not be in . Break bulk cargo is transported in , , , , or . of items secur..
A coupling (or a coupler) is a mechanism for connecting rolling stock in a train. The design of the coupler is standard, and is almost as important as the track gauge, since flexibility and convenience are maximised if all rolling stock can be coupled together.
